POVERTY AND SELF-REGULATION: CONNECTING PSYCHOSOCIAL PROCESSES, NEUROBIOLOGY, AND THE RISK FOR PSYCHOPATHOLOGY

Poverty and self-regulation: Connecting psychosocial processes, neurobiology, and the risk for psychopathology

In the United States, over 40% of youth under the age of 18 live at or near the federal poverty line.Several decades of research have established clear links between exposure to child poverty and the development of psychopathology, yet Accessories the mechanisms that convey this risk remain unclear.We review research in developmental science and ot

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Single-cell RNA sequencing unveils the activation of EGR1-ATF3 signaling in EGR1 + muscle stem cells during human paravertebral muscle degeneration

Background: Paravertebral muscles (PVM) degeneration (PMD) is closely associated with low back pain.Muscle stem cells (MuSCs) can promote muscle regeneration and repair.However, our understanding of the cellular composition of PVM and the key genes-mediated MuSCs functions is limited.Methods: We analyzed cells heterogeneity and identified key genes

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Effects of Lipoic Acid on High-Fat Diet-Induced Alteration of Synaptic Plasticity and Brain Glucose Metabolism: A PET/CT and 13C-NMR Study

Abstract High-fat diet (HFD)-induced obesity is accompanied by insulin resistance and compromised brain synaptic plasticity through the impairment of insulin-sensitive pathways regulating neuronal survival, learning, and memory.Lipoic acid is known to modulate the redox status of the cell and has insulin mimetic effects.This study was aimed at dete

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